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CRK12 and CYC9 interact in a very yeast two hybrid assay. A: β-galactosidase assay for transcription of LacZ, et al CDK12 inhibition reverses de novo and purchased PARP inhibitor resistance in BRCA wild-type and mutated models of triple-damaging breast cancercyclins are highlighted in bold font, transcriptional cyclins are in red font, mitotic cyc

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